Structure of PDB 8iuo Chain A

Receptor sequence
>8iuoA (length=362) Species: 208893 (Human respiratory syncytial virus A) [Search protein sequence]
MALSKVKLNDTLNKDQLLSSSKYTIQRSTGDSIDTPNYDVQKHINKLCGM
LLITEDANHKFTGLIGMLYAMSRLGREDTIKILRDAGYHVKANGVDVTTH
RQDINGKEMKFEVLTLASLTTEIQINIEIESRKSYKKMLKEMGEVAPEYR
HDSPDCGMIILCIAALVITKLAAGDRSGLTAVIRRANNVLKNEMKRYKGL
LPKDIANSFYEVFEKHPHFIDVFVHFGIAQSSTRGGSRVEGIFAGLFMNA
YGAGQVMLRWGVLAKSVKNIMLGHASVQAEMEQVVEVYEYAQKLGGEAGF
YHILNNPKASLLSLTQFPHFSSVVLGNAAGLGIMGEYRGTPRNQDLYDAA
KAYAEQLKENGV
3D structure
PDB8iuo Cryo-EM structure of the nucleocapsid-like assembly of respiratory syncytial virus.
ChainA
Resolution3.96 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 rna A K170 R184 R185 N249 G254 V256 S313 T315 E336 Y337 R338 K170 R184 R185 N249 G254 V256 S313 T315 E336 Y337 R338
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0030291 protein serine/threonine kinase inhibitor activity
Biological Process
GO:0019049 virus-mediated perturbation of host defense response
GO:0039502 symbiont-mediated suppression of host type I interferon-mediated signaling pathway
GO:0039580 symbiont-mediated suppression of host PKR/eIFalpha signaling
GO:0052170 symbiont-mediated suppression of host innate immune response
Cellular Component
GO:0019013 viral nucleocapsid
GO:0019029 helical viral capsid
GO:0030430 host cell cytoplasm
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:8iuo, PDBe:8iuo, PDBj:8iuo
PDBsum8iuo
PubMed37607909
UniProtA0A2H4WKL8

[Back to BioLiP]