Structure of PDB 8itx Chain A

Receptor sequence
>8itxA (length=138) Species: 9606 (Homo sapiens) [Search protein sequence]
PLIVPYNLPLPGGVVPRMLITILGTVKPNANRIALDFQRGNDVAFHFNPR
FNENNRRVIVCNTKLDNNWGREERQSVFPFESGKPFKIQVLVEPDHFKVA
VNDAHLLQYNHRVKKLNEISKLGISGDIDLTSASYTMI
3D structure
PDB8itx Discovery and Exploration of Monosaccharide Linked Dimers to Target Fibrosis
ChainA
Resolution1.12 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 SXP A R144 I145 A146 H158 N160 R162 N174 W181 E184 S237 G238 R32 I33 A34 H46 N48 R50 N62 W69 E72 S125 G126
Gene Ontology
Molecular Function
GO:0030246 carbohydrate binding

View graph for
Molecular Function
External links
PDB RCSB:8itx, PDBe:8itx, PDBj:8itx
PDBsum8itx
PubMed
UniProtP17931|LEG3_HUMAN Galectin-3 (Gene Name=LGALS3)

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