Structure of PDB 8isj Chain A

Receptor sequence
>8isjA (length=859) Species: 3702 (Arabidopsis thaliana) [Search protein sequence]
HIQKGKLIQPFGCLLALDEKTFKVIAYSENASELLTMAPVLGIGTDIRSL
FTAPSASALQKALGFGDVSLLNPILVHCRTSAKPFYAIIHRVTGSIIIDF
EPVKPYEVPMTAAGALQSYKLAAKAITRLQSLPSGSMERLCDTMVQEVFE
LTGYDRVMAYKFHEDDHGEVVSEVTKPGLEPYLGLHYPATDIPQAARFLF
MKNKVRMIVDCNAKHARVLQDEKLSFDLTLCGSTLRAPHSCHLQYMANMD
SIASLVMAVVVNEEDKRKRLWGLVVCHNTTPRFVPFPLRYACEFLAQVFA
IHVNKEVELDNQMVEKNILRTQTLLCDMLMRDAPLGIVSQSPNIMDLVKC
DGAALLYKDKIWKLGTTPSEFHLQEIASWLCEYHMDSTGLSTDSLHDAGF
PRALSLGDSVCGMAAVRISSKDMIFWFRSHTAGEVRWGGAKHDPRRMHPR
SSFKAFLEVVKTRSLPWKDYEMDAIHSLQLILRNAFKDMDKFTRIEGDYK
AIIQNPNPLIPPIFGTDEFGWCTEWNPAMSKLTGLKREEVIDKMLLGEVF
GTQKSCCRLKNQEAFVNLGIVLNNAVTSQDPEKVSFAFFTRGGKYVECLL
CVSKKLDREGVVTGVFCFLQLASHELQQALHVQRLAERTAVKRLKALAYI
KRQIRNPLSGIMFTRKMIEGTELGPEQRRILQTSALCQKQLSKILDDSDL
ESIIEGCLDLEMKEFTLNEVLTASTSQVMMKSNGKSVRITNETGEEVMSD
TLYGDSIRLQQVLADFMLMAVNFTPSGGQLTVSASLRKLANLEIRLTHTG
AGIPEFLLNQMFGTEEDVSEEGLSLMVSRKLVKLMNGDVQYLRQAGKSSF
IITAELAAA
3D structure
PDB8isj Structural insights into plant phytochrome A as a highly sensitized photoreceptor.
ChainA
Resolution3.0 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 O6E A D273 I274 P275 F282 R288 R318 H321 C323 H324 Y327 H372 D191 I192 P193 F200 R206 R236 H239 C241 H242 Y245 H277
Gene Ontology
Molecular Function
GO:0000155 phosphorelay sensor kinase activity
GO:0003729 mRNA binding
GO:0004672 protein kinase activity
GO:0005515 protein binding
GO:0009881 photoreceptor activity
GO:0009883 red or far-red light photoreceptor activity
GO:0016301 kinase activity
GO:0031516 far-red light photoreceptor activity
GO:0042802 identical protein binding
GO:0042803 protein homodimerization activity
Biological Process
GO:0000160 phosphorelay signal transduction system
GO:0006355 regulation of DNA-templated transcription
GO:0007165 signal transduction
GO:0009409 response to cold
GO:0009584 detection of visible light
GO:0009585 red, far-red light phototransduction
GO:0009630 gravitropism
GO:0009638 phototropism
GO:0009640 photomorphogenesis
GO:0010018 far-red light signaling pathway
GO:0010161 red light signaling pathway
GO:0010201 response to continuous far red light stimulus by the high-irradiance response system
GO:0010203 response to very low fluence red light stimulus
GO:0010218 response to far red light
GO:0016310 phosphorylation
GO:0017006 protein-tetrapyrrole linkage
GO:0017148 negative regulation of translation
GO:0046685 response to arsenic-containing substance
Cellular Component
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0016604 nuclear body
GO:0016607 nuclear speck
GO:0043231 intracellular membrane-bounded organelle

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8isj, PDBe:8isj, PDBj:8isj
PDBsum8isj
PubMed37491602
UniProtP14712|PHYA_ARATH Phytochrome A (Gene Name=PHYA)

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