Structure of PDB 8is8 Chain A

Receptor sequence
>8is8A (length=274) Species: 1570 (Halobacillus halophilus) [Search protein sequence]
DLNNAYDHCKNIIEKHSKTFSKAFAMLPKHQKRAVWAIYAFCRRADDIVD
EGENPKEELEAFAVEFDLFMEGRLETEDPCWIALQDAFERFPLDPAPFYE
MIVGQRMDLYPKTIDTKDDLLHYCYHVASTVGLMLLPVLAPGKVSRVKTG
AIELGYAMQITNILRDIGEDLDNHRIYIPKQMMIEYGYTRTDLHNKKVNE
AFIQLWEDLAQDAEHYYRNALATLPEYPVYSRTPVGGAAKMYRAIIQTVR
NNDYQVFGNYVSDQMKKQIIAEMQ
3D structure
PDB8is8 CrtMLIKE with two GsPP molecules
ChainA
Resolution2.3 Å
3D
structure
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Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 GST A Y41 C44 R45 D48 V133 N164 Y39 C42 R43 D46 V131 N162
BS02 GST A S19 F22 L156 M160 Y244 S17 F20 L154 M158 Y242
BS03 MG A N164 D168 N162 D166
BS04 MG A D48 D52 D46 D50
BS05 MG A D48 D52 D46 D50
Gene Ontology
Molecular Function
GO:0003824 catalytic activity
GO:0016740 transferase activity
GO:0016767 geranylgeranyl-diphosphate geranylgeranyltransferase activity
Biological Process
GO:0016117 carotenoid biosynthetic process

View graph for
Molecular Function

View graph for
Biological Process
External links
PDB RCSB:8is8, PDBe:8is8, PDBj:8is8
PDBsum8is8
PubMed
UniProtB9UXM0

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