Structure of PDB 8is7 Chain A

Receptor sequence
>8is7A (length=275) Species: 1570 (Halobacillus halophilus) [Search protein sequence]
MDLNNAYDHCKNIIEKHSKTFSKAFAMLPKHQKRAVWAIYAFCRRADDIV
DEGENPKEELEAFAVEFDLFMEGRLETEDPCWIALQDAFERFPLDPAPFY
EMIVGQRMDLYPKTIDTKDDLLHYCYHVASTVGLMLLPVLAPGKVSRVKT
GAIELGYAMQITNILRDIGEDLDNHRIYIPKQMMIEYGYTRTDLHNKKVN
EAFIQLWEDLAQDAEHYYRNALATLPEYPVYSRTPVGGAAKMYRAIIQTV
RNNDYQVFGNYVSDQMKKQIIAEMQ
3D structure
PDB8is7 CrtMLIKE with two FsPP molecules.
ChainA
Resolution1.6 Å
3D
structure
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Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 FPS A F26 Y41 C44 R45 D48 V129 V133 Q161 F25 Y40 C43 R44 D47 V128 V132 Q160
BS02 FPS A F22 R45 V133 G134 L156 M160 N164 F21 R44 V132 G133 L155 M159 N163
BS03 MG A D48 D52 D47 D51
BS04 MG A D48 D52 D47 D51
BS05 MG A N164 D168 N163 D167
Gene Ontology
Molecular Function
GO:0003824 catalytic activity
GO:0016740 transferase activity
GO:0016767 geranylgeranyl-diphosphate geranylgeranyltransferase activity
Biological Process
GO:0016117 carotenoid biosynthetic process

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Molecular Function

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Biological Process
External links
PDB RCSB:8is7, PDBe:8is7, PDBj:8is7
PDBsum8is7
PubMed
UniProtB9UXM0

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