Structure of PDB 8iro Chain A

Receptor sequence
>8iroA (length=540) Species: 3702 (Arabidopsis thaliana) [Search protein sequence]
PKLLNRLNTYVGSSRVGKRFKLAERNSTFTTELRAGTATFLTMAYILAVN
ASILSDSGGTCSVSDCIPLCSNPAIEPSQCTGPGLRLIQPDVSCKFNPVN
PGYAACVEEIRKDLIVATVAASLIGCVIMGLMANLPLALAPGMGTNAYFA
YTVVGFHGSGSISYRTALAAVFIEGLIFLFISAIGFRAKLAKLVPKPVRI
SSSAGIGLFLAFIGLQNNQGIGLVGYSPSTLVTLAACPASSRISLAPVIT
SANGTVSLLAGGSVSGDIMCIHGRMESPTFWLGIVGFVIIAYCLVKNVKG
AMIYGIVFVTAVSWFRNTEVTAFPNTSAGDAAHDYFKKIVDVHVIKHTAG
ALSFSGINKGHFWEALVTFLYVDILDTTGTLYSMARFAGFVDEKGDFAGQ
YFAFMSDASAIVIGSLLGTSPVTVFIESSTGIREGGRTGLTAITVAVYFL
LAMFFTPLLASIPAWAVGPPLILVGVMMMKSVTEIDWEDMREAIPAFVTM
ILMPLTYSVAYGLIGGIGSYVVLHLWDWGEEGLVKLGFLK
3D structure
PDB8iro Structures and mechanisms of the Arabidopsis cytokinin transporter AZG1.
ChainA
Resolution2.7 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 ZEA A G159 M160 G161 D393 T440 V441 F442 I443 E444 M495 G142 M143 G144 D376 T423 V424 F425 I426 E427 M478
Gene Ontology
Molecular Function
GO:0005345 purine nucleobase transmembrane transporter activity
GO:0015205 nucleobase transmembrane transporter activity
GO:0022857 transmembrane transporter activity
Biological Process
GO:0006863 purine nucleobase transport
GO:0015853 adenine transport
GO:0015854 guanine transport
GO:0055085 transmembrane transport
GO:1904823 purine nucleobase transmembrane transport
Cellular Component
GO:0005829 cytosol
GO:0016020 membrane

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Molecular Function

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Cellular Component
External links
PDB RCSB:8iro, PDBe:8iro, PDBj:8iro
PDBsum8iro
PubMed38172575
UniProtQ9SRK7|AZG1_ARATH Adenine/guanine permease AZG1 (Gene Name=AZG1)

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