Structure of PDB 8iqt Chain A

Receptor sequence
>8iqtA (length=254) Species: 9606 (Homo sapiens) [Search protein sequence]
DSLRPKLSEEQQRIIAILLDAHHKTYDPTYSDFCQFRPPVRVNDGGSVTL
ELSQLSMLPHLADLVSYSIQKVIGFAKMIPGFRDLTSEDQIVLLKSSAIE
VIMLRSNESFTMDDMSWTCGNQDYKYRVSDVTKAGHSLELIEPLIKFQVG
LKKLNLHEEEHVLLMAICIVSPDRPGVQDAALIEAIQDRLSNTLQTYIRC
RHPPPGSHLLYAKMIQKLADLRSLNEEHSKQYRCLSFQPECSMKLTPLVL
EVFG
3D structure
PDB8iqt Crystal structure of the human vitamin D receptor ligand binding domain complexed with (23R)-F-25(OH)D3
ChainA
Resolution1.745 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 SV0 A Y143 S237 I271 S275 S278 W286 C288 H305 H397 Y26 S68 I102 S106 S109 W117 C119 H136 H228
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0004879 nuclear receptor activity
Biological Process
GO:0006355 regulation of DNA-templated transcription
Cellular Component
GO:0005634 nucleus

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8iqt, PDBe:8iqt, PDBj:8iqt
PDBsum8iqt
PubMed
UniProtP11473|VDR_HUMAN Vitamin D3 receptor (Gene Name=VDR)

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