Structure of PDB 8iql Chain A

Receptor sequence
>8iqlA (length=140) Species: 9606 (Homo sapiens) [Search protein sequence]
YDNREIVMKYIHYKLSQRGYEWDAESEVVHLTLRQAGDDFSRRYRRDFAE
MSSQLHLTPFTARGRFATVVEELFRDGVNWGRIVAFFEFGGVMCVESVNR
EMSPLVDNIALWMTEYLNRHLHTWIQDNGGWDAFVELYGP
3D structure
PDB8iql Structural basis of the specificity and interaction mechanism of Bmf binding to pro-survival Bcl-2 family proteins.
ChainA
Resolution2.9577 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A F104 Y108 M115 V133 E136 N143 G145 R146 A149 Y202 F40 Y44 M51 V69 E72 N79 G81 R82 A85 Y138
Gene Ontology
Biological Process
GO:0042981 regulation of apoptotic process
GO:0043066 negative regulation of apoptotic process

View graph for
Biological Process
External links
PDB RCSB:8iql, PDBe:8iql, PDBj:8iql
PDBsum8iql
PubMed37560128
UniProtP10415|BCL2_HUMAN Apoptosis regulator Bcl-2 (Gene Name=BCL2);
Q07817|B2CL1_HUMAN Bcl-2-like protein 1 (Gene Name=BCL2L1)

[Back to BioLiP]