Structure of PDB 8ipt Chain A

Receptor sequence
>8iptA (length=588) Species: 469008 (Escherichia coli BL21(DE3)) [Search protein sequence]
MNKSRQKELTRWLKQQSVISQRWLNISRLLGFVSGILIIAQAWFMARILQ
HMIMENIPREALLLPFTLLVLTFVLRAWVVWLRERVGYHAGQHIRFAIRR
QVLDRLQQAGPAWIQGKPAGSWATLVLEQIDDMHDYYARYLPQMALAVSV
PLLIVVAIFPSNWAAALILLGTAPLIPLFMALVGMGAADANRRNFLALAR
LSGHFLDRLRGMETLRIFGRGEAEIESIRSASEDFRQRTMEVLRLAFLSS
GILEFFTSLSIALVAVYFGFSYLGELDFGHYDTGVTLAAGFLALILAPEF
FQPLRDLGTFYHAKAQAVGAADSLKTFMETPLAHPQRGEAELALTDPLTI
EAEDLFITSPEGKTLAGPLNFTLPAGQRAVLVGRSGSGKSSLLNALSGFL
SYQGSLRINGIELRDLSPESWRKHLSWVGQNPQLPAATLRDNVLLARPDA
SEQELQAALDNAWVSEFLPLLPQGVDTPVGDQAARLSVGQAQRVAVARAL
LNPCSLLLLDQPAASLDAHSEQRVMEALNAASLRQTTLMVTHQLEDLADW
DVIWVMQDGRIIEQGRYAELSVAGGPFATLLAHRQEEI
3D structure
PDB8ipt Cryo-EM structures of a prokaryotic heme transporter CydDC.
ChainA
Resolution3.5 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 7.4.2.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ATP A A484 R485 A484 R485
BS02 ATP A S359 S385 G386 S387 G388 K389 S390 S391 S359 S385 G386 S387 G388 K389 S390 S391
Gene Ontology
Molecular Function
GO:0005524 ATP binding
GO:0015439 ABC-type heme transporter activity
GO:0016887 ATP hydrolysis activity
GO:0034040 ATPase-coupled lipid transmembrane transporter activity
GO:0140359 ABC-type transporter activity
Biological Process
GO:0006865 amino acid transport
GO:0006869 lipid transport
GO:0033228 cysteine export across plasma membrane
GO:0034775 glutathione transmembrane transport
GO:0035351 heme transmembrane transport
GO:0042883 cysteine transport
GO:0045454 cell redox homeostasis
GO:0055085 transmembrane transport
GO:1903605 cytochrome biosynthetic process
Cellular Component
GO:0005886 plasma membrane
GO:0016020 membrane
GO:0043190 ATP-binding cassette (ABC) transporter complex
GO:0055051 ATP-binding cassette (ABC) transporter complex, integrated substrate binding

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8ipt, PDBe:8ipt, PDBj:8ipt
PDBsum8ipt
PubMed37144855
UniProtP29018|CYDD_ECOLI Glutathione/L-cysteine transport system ATP-binding/permease protein CydD (Gene Name=cydD)

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