Structure of PDB 8ij9 Chain A

Receptor sequence
>8ij9A (length=168) Species: 10090 (Mus musculus) [Search protein sequence]
GNPLRKFKLVFLGEQSVGKTSLITRFMYDSFDNTYQATIGIDFLSKTMYL
EDRTVRLQLWDTAGLERFRSLIPSYIRDSTVAVVVYDITNLNSFQQTSKW
IDDVRTERGSDVIIMLVGNKTDLADKRQITIEEGEQRAKELSVMFIETSA
KTGYNVKQLFRRVASALP
3D structure
PDB8ij9 Structural basis of ELKS/Rab6B interaction and its role in vesicle capturing enhanced by liquid-liquid phase separation.
ChainA
Resolution2.04 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.6.5.2: small monomeric GTPase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 GTP A S23 G25 K26 T27 S28 F38 N40 Y42 A44 T45 G71 N126 K127 D129 L130 S156 A157 K158 S16 G18 K19 T20 S21 F31 N33 Y35 A37 T38 G64 N119 K120 D122 L123 S149 A150 K151
BS02 MG A T27 T45 T20 T38
Gene Ontology
Molecular Function
GO:0003924 GTPase activity
GO:0005525 GTP binding

View graph for
Molecular Function
External links
PDB RCSB:8ij9, PDBe:8ij9, PDBj:8ij9
PDBsum8ij9
PubMed37172719
UniProtP61294|RAB6B_MOUSE Ras-related protein Rab-6B (Gene Name=Rab6b)

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