Structure of PDB 8iit Chain A

Receptor sequence
>8iitA (length=206) Species: 246196 (Mycolicibacterium smegmatis MC2 155) [Search protein sequence]
AGAQDFVPHTADLAELAAAAGECRGCGLYRDATQAVFGAGGRSARIMMIG
EQPGDKEDLAGLPFVGPAGRLLDRALEAADIDRDALYVTNAVKHFKFTRA
AGGKRRISKTPSRTEVVACRPWLIAEMTSVEPDVVVLLGATAAKALLGND
FRVTQHRGEVLHVDDVPGDPALVATVHPSSLLAGPKEERESAFAGLVDDL
RVAADV
3D structure
PDB8iit Mutational and structural analyses of UdgX: insights into the active site pocket architecture and its evolution.
ChainA
Resolution1.61 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.2.2.27: uracil-DNA glycosylase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 SF4 A C24 G26 C27 H95 A119 C120 W123 C23 G25 C26 H94 A118 C119 W122
BS02 URA A E52 Q53 E58 P64 F65 N91 H178 E51 Q52 E57 P63 F64 N90 H177
Gene Ontology
Molecular Function
GO:0004844 uracil DNA N-glycosylase activity
GO:0046872 metal ion binding
GO:0051539 4 iron, 4 sulfur cluster binding
GO:0097506 deaminated base DNA N-glycosylase activity
Biological Process
GO:0006281 DNA repair

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Molecular Function
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Biological Process
External links
PDB RCSB:8iit, PDBe:8iit, PDBj:8iit
PDBsum8iit
PubMed37283083
UniProtA0QP43

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