Structure of PDB 8iht Chain A

Receptor sequence
>8ihtA (length=121) Species: 8355 (Xenopus laevis) [Search protein sequence]
ARTKQTARKSTGGKAPRKQLATKAPHRYRPGTVALREIRRYQKSTELLIR
KLPFQRLVREIAQDFKTDLRFQSSAVMALQEASEAYLVALFEDTNLAAIH
AKRVTIMPKDIQLARRIRGER
3D structure
PDB8iht Structural basis for nucleosome binding and catalysis by the yeast Rpd3S/HDAC holoenzyme.
ChainA
Resolution3.72 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna A Y41 R42 T45 R63 R72 R83 F84 Q85 S86 R116 V117 Y28 R29 T32 R50 R59 R70 F71 Q72 S73 R103 V104
BS02 dna A H39 R40 Y41 V46 R49 R63 K64 L65 P66 R83 H26 R27 Y28 V33 R36 R50 K51 L52 P53 R70
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0005515 protein binding
GO:0030527 structural constituent of chromatin
GO:0046982 protein heterodimerization activity
Cellular Component
GO:0000786 nucleosome
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005694 chromosome

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Molecular Function
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Cellular Component
External links
PDB RCSB:8iht, PDBe:8iht, PDBj:8iht
PDBsum8iht
PubMed37845487
UniProtP84233|H32_XENLA Histone H3.2

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