Structure of PDB 8ifx Chain A

Receptor sequence
>8ifxA (length=328) Species: 63363 (Aquifex aeolicus) [Search protein sequence]
MRTLAVETSCDETALAIYDDQKGVLGNVILSQAVVHSPFGGVVPELSARE
HTRNILPIFDRLLKESRINLEEIDFISFTLTPGLILSLVVGVAFAKALAY
EYRKPLVPVHHLEGHIYSVFLEKKVEYPFLALIISGGHTDLYLVRDFGRY
DFLGGTLDDAVGEAYDKVAKMLGLGYPGGPIIDRLAKEGKKLYPLPKPLM
EEGNLNFSFSGLKTAILNLRKEDIAYSFQETVVEILLEKSLWAMKKTGIK
RLVVVGGVSANSRLREVFKKASQEYGFELYIPHPSLSTDNALMIAYAGME
RFKRGVVAPLDVNPQPNIPLEEFGRIWT
3D structure
PDB8ifx Crystal structure of Aquifex aeolicus TsaD-TsaB in complex with ADP
ChainA
Resolution2.0 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.3.1.234: N(6)-L-threonylcarbamoyladenine synthase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 FE A H111 H115 D296 H111 H115 D289
BS02 ADP A C10 H115 S135 G136 G179 P180 G264 V265 N268 D296 C10 H115 S135 G136 G179 P180 G257 V258 N261 D289
Gene Ontology
Molecular Function
GO:0005506 iron ion binding
GO:0016746 acyltransferase activity
GO:0016747 acyltransferase activity, transferring groups other than amino-acyl groups
GO:0046872 metal ion binding
GO:0061711 N(6)-L-threonylcarbamoyladenine synthase activity
Biological Process
GO:0002949 tRNA threonylcarbamoyladenosine modification
GO:0006400 tRNA modification
GO:0008033 tRNA processing
GO:0070525 tRNA threonylcarbamoyladenosine metabolic process
Cellular Component
GO:0005737 cytoplasm

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8ifx, PDBe:8ifx, PDBj:8ifx
PDBsum8ifx
PubMed
UniProtO66986|TSAD_AQUAE tRNA N6-adenosine threonylcarbamoyltransferase (Gene Name=tsaD)

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