Structure of PDB 8ifk Chain A

Receptor sequence
>8ifkA (length=414) Species: 1393122 (Thermoflavifilum thermophilum) [Search protein sequence]
RNKIFISHATPEDDDFTRWLSLKLIGLGYEVWCDILFLDKFWSTIEKEIR
ENTCKFLIVSSTAGNKREGVLKELAVATKVKKHLQDDMFIIPLAIDENLS
YDDINIEIVRLIDFKKSWAKGLQDLLDAFEKQNVPKKPPDHSKSNLLYQQ
IFLHDKQAIEKEETYDSNWFPIISFPNELRFHRYDWRLPKQFDVRTLAFP
AIRYKEYLCTFAWEYDFIHQLPKTETYNGQESIRISTSDILSGRYDTDFI
RNYECQRLIVQLINKAFELRMKDKNVREYQMSKTFAYWIEKGKLEKDKFE
KIKLVGKQKNKYWHFGISAAGKLYPSPVLMVSSHIIFTMDGINLIKSKSI
QHSSRRKQGKNWWNDKWREKLLAFIRFLSDDQNAIYLNVGSEEKILISNK
PLKFFGKMSYVTPS
3D structure
PDB8ifk Target ssDNA activates the NADase activity of prokaryotic SPARTA immune system.
ChainA
Resolution2.54 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 rna A K196 Y210 K211 Y259 E260 M287 S288 K289 H340 K354 H358 R361 R362 K190 Y204 K205 Y253 E254 M281 S282 K283 H334 K348 H352 R355 R356
BS02 dna A R201 R263 V266 Q267 N270 K328 H358 S359 R362 K366 W369 R195 R257 V260 Q261 N264 K322 H352 S353 R356 K360 W363
Gene Ontology
Biological Process
GO:0007165 signal transduction

View graph for
Biological Process
External links
PDB RCSB:8ifk, PDBe:8ifk, PDBj:8ifk
PDBsum8ifk
PubMed37932528
UniProtA0A1I7NFG5

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