Structure of PDB 8iej Chain A

Receptor sequence
>8iejA (length=60) Species: 9606 (Homo sapiens) [Search protein sequence]
EYKARLTCPCCNTRKKDAVLTKCFHVFCFECVRGRYEARQRKCPKCNAAF
GAHDFHRIYI
3D structure
PDB8iej Mechanistic insights into nucleosomal H2B monoubiquitylation mediated by yeast Bre1-Rad6 and its human homolog RNF20/RNF40-hRAD6A.
ChainA
Resolution3.12 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.3.2.27: RING-type E3 ubiquitin transferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZN A C948 C951 C968 C971 C8 C11 C28 C31
BS02 ZN A H965 C983 H25 C43
Gene Ontology
Molecular Function
GO:0004842 ubiquitin-protein transferase activity
GO:0046872 metal ion binding

View graph for
Molecular Function
External links
PDB RCSB:8iej, PDBe:8iej, PDBj:8iej
PDBsum8iej
PubMed37633270
UniProtO75150|BRE1B_HUMAN E3 ubiquitin-protein ligase BRE1B (Gene Name=RNF40)

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