Structure of PDB 8ie5 Chain A

Receptor sequence
>8ie5A (length=271) Species: 9606 (Homo sapiens) [Search protein sequence]
TVFRQENVDDYYDTGEELGSGQFAVVKKCREKSTGLQYAAKFIKKRRTKS
SRRGVSREDIEREVSILKEIQHPNVITLHEVYENKTDVILILELVAGGEL
FDFSLTEEEATEFLKQILNGVYYLHSLQIAHFDLKPENIMLLDRNVPKPR
IKIIDFGLAHKIDFGNEFKNIFGTPEFVAPEIVNYEPLGLEADMWSIGVI
TYILLSGASPFLGDTKQETLANVSAVNYEFEDEYFSNTSALAKDFIRRLL
VKDPKKRMTIQDSLQHPWIKP
3D structure
PDB8ie5 Characterization of the molecular interactions between resveratrol derivatives and death-associated protein kinase 1.
ChainA
Resolution1.803 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.11.1: non-specific serine/threonine protein kinase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 EZE A A40 K42 E64 I77 L93 E94 L95 V96 I160 D161 F162 A39 K41 E63 I76 L92 E93 L94 V95 I154 D155 F156
Gene Ontology
Molecular Function
GO:0004672 protein kinase activity
GO:0005524 ATP binding
Biological Process
GO:0006468 protein phosphorylation

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:8ie5, PDBe:8ie5, PDBj:8ie5
PDBsum8ie5
PubMed37171222
UniProtP53355|DAPK1_HUMAN Death-associated protein kinase 1 (Gene Name=DAPK1)

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