Structure of PDB 8idy Chain A

Receptor sequence

>8idyA (length=307) Species: 9606 (Homo sapiens) [Search protein sequence]

DMQSLIENAEMSTESYDQGKDRDLVTEDTGVRNEAQEEIYKKGQSKRIWG
ELYKVIDSSDVVVQVLDARDPMGTRSPHIETYLKKEKPWKHLIFVLNKCD
LVPTWATKRWVAVLSQDYPTLAFHASLTNPFGKGAFIQLLRQFGKLHTDK
KQISVGFIGYPNVGKSSVINTLRSKKVCNVAPIAGETKVWQYITLMRRIF
LIDCPGVVYPSEDSETDIVLKGVVQVEKIKSPEDHIGAVLERAKPEYISK
TYKIDSWENAEDFLEKLAFRTGKLLKGGEPDLQTVGKMVLNDWQRGRIPF
FVKPPNA

3D structure

PDB

8idy Visualizing the nucleoplasmic maturation of human pre-60S ribosomal particles.

Chain

Resolution

3.0 Å

3D
structure

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Enzymatic activity

Enzyme Commision number

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	rna	A	K204 R205 D215 D218 R299 K308 Q310 K333 V335 P340 V347 Y350 T352 M354 R355 E385 R428 T429 K431 L432 L433 K434 G435 R453 R455	K46 R47 D57 D60 R141 K150 Q152 K175 V177 P182 V189 Y192 T194 M196 R197 E227 R270 T271 K273 L274 L275 K276 G277 R295 R297
BS02	GDP	A	N255 K256 D258 H282 A283 N320 G322 K323 S324 S325 P340	N97 K98 D100 H124 A125 N162 G164 K165 S166 S167 P182

Gene Ontology

	Molecular Function
GO:0003723	RNA binding
GO:0003924	GTPase activity
GO:0005525	GTP binding

	Biological Process
GO:0008150	biological_process
GO:0042254	ribosome biogenesis

	Cellular Component
GO:0005634	nucleus
GO:0005730	nucleolus
GO:0016020	membrane

View graph for
Molecular Function

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Biological Process

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Cellular Component

External links

PDB	RCSB:8idy, PDBe:8idy, PDBj:8idy
PDBsum	8idy
PubMed	37491604
UniProt	Q13823\|NOG2_HUMAN Nucleolar GTP-binding protein 2 (Gene Name=GNL2)

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