Structure of PDB 8iaz Chain A

Receptor sequence

>8iazA (length=384) Species: 2292895 (Firmicutes bacterium AM43-11BH) [Search protein sequence]

LLKSFKTEINPSEEQKVKIHKTIGTCRFIYNFYLAHNKELYDKGEKFMSG
KSFSVWLNNEYLPQNPDKLWIKEVSSKSVKHSIENGCIAFTRFFKHQSAF
PNLKKKGKSDVKMYFVKNNPKDCRCERHRINIPSLGWVRIKEKGYIPTTK
DGYVIKSGTVSMKADRYYVSVLVEISNNKIANNSNAGIGIDLGLKDFAIV
SNGKTYKNINKSARLKKHEKQLIREQRSLSRKYENLKKGESTQKANIQKQ
RLKVQKLHHRMDNIRTDYINKTIAEIVKTKPSYITIEDLNVKGMMKNRHL
SKAVASQKFYEFRTKLQAKCNENGIELRVVDRWYPSSKTCHCCGAVKKDL
KLSDRIFKCSCGYVEDRAFNAALNLRDAITYEVA

3D structure

PDB

8iaz Discovery and structural mechanism of DNA endonucleases guided by RAGATH-18-derived RNAs.

Chain

Resolution

3.0 Å

3D
structure

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Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)
BS01	rna	A	S7 K9 E11 A92 R95 S101 A102 P104 N105 K107 K115 R130 H131 R132 W140 R142 K144 E145 K146 Y148 R169 A216 R217 K219 K220 K223 R227 Q229 R230 S233 R234 K235 N238 Q246 N249 R263 D270 K274 R301 H302 K322 W336 K354	S4 K6 E8 A89 R92 S98 A99 P101 N102 K104 K112 R127 H128 R129 W137 R139 K141 E142 K143 Y145 R166 A213 R214 K216 K217 K220 R224 Q226 R227 S230 R231 K232 N235 Q243 N246 R260 D267 K271 R298 H299 K319 W333 K351
BS02	dna	A	L5 K80 R95 Q100 Y117 S160 Y236 R254 Q258 D265 K311 Y313	L2 K77 R92 Q97 Y114 S157 Y233 R251 Q255 D262 K308 Y310
BS03	dna	A	K41 Y44 S52 K54 N61 N62 S79 K83 F96 F103 N121 N122 P136	K38 Y41 S49 K51 N58 N59 S76 K80 F93 F100 N118 N119 P133
BS04	ZN	A	C343 C364	C340 C361

External links

PDB	RCSB:8iaz, PDBe:8iaz, PDBj:8iaz
PDBsum	8iaz
PubMed	38575718

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