Structure of PDB 8iab Chain A

Receptor sequence
>8iabA (length=704) Species: 3702 (Arabidopsis thaliana) [Search protein sequence]
TPLALVGAKVSHIESLDYEINENDLFKHDWRSRSKAQVFQYIFLKWTLAC
LVGLFTGLIATLINLAVENIAGYKLLAVGYYIAQDRFWTGLMVFTGANLG
LTLVATVLVVYFAPTAAGPGIPEIKAYLNGIDTPNMFGFTTMMVKIVGSI
GAVAAGLDLGKEGPLVHIGSCIASLLGQGGPDNHRIKWRWLRYFNNDRDR
RDLITCGSASGVCAAFRSPVGGVLFALEEVATWWRSALLWRTFFSTAVVV
VVLRAFIEICNSGKCGLFGSGGLIMFDVSHVEVRYHAADIIPVTLIGVFG
GILGSLYNHLLHKVLRLYNLINQKGKIHKVLLSLGVSLFTSVCLFGLPFL
AECKPCKQFNCPNGYYNDLSTLLLTTNDDAVRNIFSSNTPNEFGMVSLWI
FFGLYCILGLITFGIATPSGLFLPIILMGSAYGRMLGTAMGSYTNIDQGL
YAVLGAASLMAGSMRMTVSLCVIFLELTNNLLLLPITMFVLLIAKTVGDS
FNLSIYEIILHLKGLPFLEANPEPWMRNLTVGELNDAKPPVVTLNGVEKV
ANIVDVLRNTTHNAFPVLDGGTELHGLILRAHLVKVLKKRWFLNEKRRTE
EWEVREKFTPVELAEREDNFDDVAITSSEMQLYVDLHPLTNTTPYTVVQS
MSVAKALVLFRSVGLRHLLVVPKIQASGMSPVIGILTRQDLRAYNILQAF
PHLD
3D structure
PDB8iab Molecular mechanism underlying regulation of Arabidopsis CLCa transporter by nucleotides and phospholipids.
ChainA
Resolution2.96 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ATP A E55 S56 K596 V599 V600 H620 N621 R729 H730 I748 T750 D753 E14 S15 K538 V541 V542 H562 N563 R666 H667 I685 T687 D690
BS02 PIO A R72 K86 W87 R276 R31 K45 W46 R235
BS03 CL A G201 E203 G478 G160 E162 G420
BS04 CL A P160 Y564 P119 Y506
BS05 CL A P160 G161 E164 P119 G120 E123
BS06 PIO A L550 T554 N579 L492 T496 N521
Gene Ontology
Molecular Function
GO:0005247 voltage-gated chloride channel activity
GO:0005254 chloride channel activity
GO:0005515 protein binding
GO:0015112 nitrate transmembrane transporter activity
Biological Process
GO:0006821 chloride transport
GO:0010167 response to nitrate
GO:0015706 nitrate transmembrane transport
GO:0034220 monoatomic ion transmembrane transport
GO:0055085 transmembrane transport
GO:1902476 chloride transmembrane transport
Cellular Component
GO:0016020 membrane
GO:0034707 chloride channel complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8iab, PDBe:8iab, PDBj:8iab
PDBsum8iab
PubMed37573431
UniProtP92941|CLCA_ARATH Chloride channel protein CLC-a (Gene Name=CLC-A)

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