Structure of PDB 8ia5 Chain A

Receptor sequence
>8ia5A (length=86) Species: 9606 (Homo sapiens) [Search protein sequence]
QINQVRPKLPLLKILHAAGAQGEMFTVKEVMHYLGQYIMVKQLYDQQEQH
MVYCGGDLLGELLGRQSFSVKDPSPLYDMLRKNLVT
3D structure
PDB8ia5 Small peptide enhances the binding of nutline-3a to N-terminal domain of MdmX
ChainA
Resolution1.93 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A K49 M52 Y98 K28 M31 Y77
BS02 NUT A M52 I59 M60 Q70 V91 P94 L97 M31 I38 M39 Q49 V70 P73 L76
Gene Ontology
Biological Process
GO:0043066 negative regulation of apoptotic process
GO:0051726 regulation of cell cycle
Cellular Component
GO:0005634 nucleus

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Biological Process
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Cellular Component
External links
PDB RCSB:8ia5, PDBe:8ia5, PDBj:8ia5
PDBsum8ia5
PubMed
UniProtO15151|MDM4_HUMAN Protein Mdm4 (Gene Name=MDM4)

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