Structure of PDB 8i8h Chain A

Receptor sequence
>8i8hA (length=280) Species: 2001 (Streptosporangium roseum) [Search protein sequence]
MGILQANRVLLSRLLPGVEPEGLTVRHGQFHQVVIASDRVVCLPRTAAAA
ARLPRRAAVMRVLAGLDLGCRTPRPLCEGSLPFLVLSRVPGAPLEADALE
DSKVAEVVAAQYVTLLSGLASAGADEKVRAALPAPQGRWRQFAADVRAEL
FPLMSDGGCRQAERELAALDSLPDITEAVVHGNLGAENVLWVRDDGLPRL
SGVIDWDEVSIGDPAEDLAAIGAGYGKDFLDQVLTLGGWSDRRMATRIAT
IRATFALQQALSACRDGDEEELADGLTGYR
3D structure
PDB8i8h Discovery and characterization of genes conferring natural resistance to the antituberculosis antibiotic capreomycin.
ChainA
Resolution2.02 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.1.103: viomycin kinase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A W145 G188 N189 G191 E193 E214 E222 F261 Q264 Q265 W139 G182 N183 G185 E187 E208 E216 F255 Q258 Q259
BS02 ATP A G28 Q29 F30 H31 P73 R94 I210 D211 D213 E214 G28 Q29 F30 H31 P73 R88 I204 D205 D207 E208
Gene Ontology
Molecular Function
GO:0005524 ATP binding
GO:0005525 GTP binding
GO:0016301 kinase activity
GO:0050394 viomycin kinase activity
Biological Process
GO:0016310 phosphorylation

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Molecular Function
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Biological Process
External links
PDB RCSB:8i8h, PDBe:8i8h, PDBj:8i8h
PDBsum8i8h
PubMed38114770
UniProtD2B3F1

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