Structure of PDB 8i8g Chain A

Receptor sequence
>8i8gA (length=280) Species: 2001 (Streptosporangium roseum) [Search protein sequence]
GILQANRVLLSRLLPGVEPEGLTVRHGQFHQVVIASDRVVCLPRTAAAAA
RLPRRAAVMRVLAGLDLGCRTPRPLCEGSALPFLVLSRVPGAPLEADALE
DSKVAEVVAAQYVTLLSGLASAGADEKVRAALPAPQGRWRQFAADVRAEL
FPLMSDGGCRQAERELAALDSLPDITEAVVHGNLGAENVLWVRDDGLPRL
SGVIDWDEVSIGDPAEDLAAIGAGYGKDFLDQVLTLGGWSDRRMATRIAT
IRATFALQQALSACRDGDEEELADGLTGYR
3D structure
PDB8i8g Discovery and characterization of genes conferring natural resistance to the antituberculosis antibiotic capreomycin.
ChainA
Resolution3.0 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.1.103: viomycin kinase.
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 peptide A G188 N189 G191 D211 E214 F261 A262 Q265 G182 N183 G185 D205 E208 F255 A256 Q259
BS02 ATP A Q29 F30 H31 V33 R94 I210 D211 D213 Q28 F29 H30 V32 R88 I204 D205 D207
Gene Ontology
Molecular Function
GO:0005524 ATP binding
GO:0005525 GTP binding
GO:0016301 kinase activity
GO:0050394 viomycin kinase activity
Biological Process
GO:0016310 phosphorylation

View graph for
Molecular Function

View graph for
Biological Process
External links
PDB RCSB:8i8g, PDBe:8i8g, PDBj:8i8g
PDBsum8i8g
PubMed38114770
UniProtD2B3F1

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