Structure of PDB 8i89 Chain A

Receptor sequence
>8i89A (length=280) Species: 2001 (Streptosporangium roseum) [Search protein sequence]
MGILQANRVLLSRLLPGVEPEGLTVRHGQFHQVVIASDRVVCLPRTAAAA
ARLPRRAAVMRVLAGLDLGCRTPRPLCEGSLPFLVLSRVPGAPLEADALE
DSKVAEVVAAQYVTLLSGLASAGADEKVRAALPAPQGRWRQFAADVRAEL
FPLMSDGGCRQAERELAALDSLPDITEAVVHGNLGAENVLWVRDDGLPRL
SGVIDWDEVSIGDPAEDLAAIGAGYGKDFLDQVLTLGGWSDRRMATRIAT
IRATFALQQALSACRDGDEEELADGLTGYR
3D structure
PDB8i89 Discovery and characterization of genes conferring natural resistance to the antituberculosis antibiotic capreomycin.
ChainA
Resolution2.0 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.1.103: viomycin kinase.
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 peptide A W145 G188 N189 G191 E193 E222 A226 A229 F261 Q264 Q265 E277 W139 G182 N183 G185 E187 E216 A220 A223 F255 Q258 Q259 E271
Gene Ontology
Molecular Function
GO:0005524 ATP binding
GO:0005525 GTP binding
GO:0016301 kinase activity
GO:0050394 viomycin kinase activity
Biological Process
GO:0016310 phosphorylation

View graph for
Molecular Function

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Biological Process
External links
PDB RCSB:8i89, PDBe:8i89, PDBj:8i89
PDBsum8i89
PubMed38114770
UniProtD2B3F1

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