Structure of PDB 8i85 Chain A

Receptor sequence
>8i85A (length=280) Species: 2001 (Streptosporangium roseum) [Search protein sequence]
MGILQANRVLLSRLLPGVEPEGLTVRHGQFHQVVIASDRVVCLPRTAAAA
ARLPRRAAVMRVLAGLDLGCRTPRPLCEGSLPFLVLSRVPGAPLEADALE
DSKVAEVVAAQYVTLLSGLASAGADEKVRAALPAPQGRWRQFAADVRAEL
FPLMSDGGCRQAERELAALDSLPDITEAVVHGNLGAENVLWVRDDGLPRL
SGVIDWDEVSIGDPAEDLAAIGAGYGKDFLDQVLTLGGWSDRRMATRIAT
IRATFALQQALSACRDGDEEELADGLTGYR
3D structure
PDB8i85 Discovery and characterization of genes conferring natural resistance to the antituberculosis antibiotic capreomycin.
ChainA
Resolution2.17 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.1.103: viomycin kinase.
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 ATP A R26 G28 Q29 F30 H31 V33 P73 R94 I210 D211 D213 E214 R26 G28 Q29 F30 H31 V33 P73 R88 I204 D205 D207 E208
Gene Ontology
Molecular Function
GO:0005524 ATP binding
GO:0005525 GTP binding
GO:0016301 kinase activity
GO:0050394 viomycin kinase activity
Biological Process
GO:0016310 phosphorylation

View graph for
Molecular Function

View graph for
Biological Process
External links
PDB RCSB:8i85, PDBe:8i85, PDBj:8i85
PDBsum8i85
PubMed38114770
UniProtD2B3F1

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