Structure of PDB 8i7h Chain A

Receptor sequence
>8i7hA (length=297) Species: 585 (Proteus vulgaris) [Search protein sequence]
TKIKVAIVGYGNIGRFALEAVQAAQDFELVGVVRRDINNVPEELQNITVT
NDIKTLGDVDVALLCSPTRAIKELAKSILSLGINTVDSFDVHSEIVSLKT
ELDDVAKKHDRVAVISAGWDPGSDSIVRTLMLAMAPKGITYTNFGPGMSM
GHSVAAKAIEGVKDALSMTIPLGTGVHRRMVYVELEAGANFNQVEQAIKA
DSYFSSDETHVKQVDSVDSLKDVGHGVHMTHKGVSGKTHNQLFEYSMRIN
NPALTSQFMVSAARASMKQRAGAYTVIEIPPVDFLAGDLNTLIAKLV
3D structure
PDB8i7h Analysis of the catalytic mechanism of meso-DAPDH and extension of D-aromatic amino acid substrate scope
ChainA
Resolution3.02 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 1.4.1.16: diaminopimelate dehydrogenase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 API A S151 M152 G153 H154 S149 M150 G151 H152
BS02 API A W121 D122 F146 T257 W119 D120 F144 T255
Gene Ontology
Molecular Function
GO:0000166 nucleotide binding
GO:0016491 oxidoreductase activity
GO:0047850 diaminopimelate dehydrogenase activity
Biological Process
GO:0009085 lysine biosynthetic process
GO:0009089 lysine biosynthetic process via diaminopimelate
GO:0019877 diaminopimelate biosynthetic process

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:8i7h, PDBe:8i7h, PDBj:8i7h
PDBsum8i7h
PubMed
UniProtA0A379F6K8

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