Structure of PDB 8i6k Chain A

Receptor sequence
>8i6kA (length=183) Species: 9606 (Homo sapiens) [Search protein sequence]
DPVTVVVLKATAPFKYESGKSTMFHATVASKTQYFHVKVFDINLKEKFVR
KKVITISDYSECKGVMEIKEASSVSDFNQNFEVPNRIIEIANKTPKISQL
YKQASGTMVYGLFMLQKKSVHKKNTIYEIQDNTGSMDVVGSGKWHNIKCE
KGDKLRLFCLQLRTVDRKLKLVCGSHSFIKVIK
3D structure
PDB8i6k Structural mechanism of dsDNA recognition by the hMNDA HIN domain: New insights into the DNA-binding model of a PYHIN protein.
ChainA
Resolution2.4 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna A K218 R262 R368 K9 R50 R156
Gene Ontology
Biological Process
GO:0002218 activation of innate immune response
GO:0035458 cellular response to interferon-beta

View graph for
Biological Process
External links
PDB RCSB:8i6k, PDBe:8i6k, PDBj:8i6k
PDBsum8i6k
PubMed37348588
UniProtP41218|MNDA_HUMAN Myeloid cell nuclear differentiation antigen (Gene Name=MNDA)

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