Structure of PDB 8i5m Chain A

Receptor sequence
>8i5mA (length=310) Species: 10116 (Rattus norvegicus) [Search protein sequence]
RRRVLTKDGRSNVRMEHIADKRFLYLKDLWTTFIDMQWRYKLLLFSATFA
GTWFLFGVVWYLVAVAHGDLLELGPPANHTPCVVQVHTLTGAFLFSLESQ
TTIGYGFRYISEECPLAIVLLIAQLVLTTILEIFITGTFLAKIARPKKRA
ETIRFSQHAVVAYHNGKLCLMIRVANMRKSLLIGCQVTGKLLQTHQTKEG
ENIRLNQVNVTFQVDTASDSPFLILPLTFYHVVDETSPLKDLPLRSGEGD
FELVLILSGTVESTSATCQVRTSYLPEEILWGYEFTPAISLSASGKYVAD
FSLFDQVVKV
3D structure
PDB8i5m Pharmacological inhibition of astrocytic Kir4.1 channel evokes rapid-onset antidepressant responses
ChainA
Resolution2.85 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 PIO A R36 Q63 W64 R65 K168 R171 K173 R10 Q37 W38 R39 K142 R145 K147
Gene Ontology
Molecular Function
GO:0005242 inward rectifier potassium channel activity
Biological Process
GO:0006813 potassium ion transport
Cellular Component
GO:0016020 membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8i5m, PDBe:8i5m, PDBj:8i5m
PDBsum8i5m
PubMed38355723
UniProtP49655|KCJ10_RAT ATP-sensitive inward rectifier potassium channel 10 (Gene Name=Kcnj10)

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