Structure of PDB 8i16 Chain A

Receptor sequence
>8i16A (length=639) Species: 1410628 (Lachnospiraceae bacterium ND2006) [Search protein sequence]
VSPRPRPRYREERTLVRKLLPRPGQSKQEFRENVKKLRKAFLQFNADVSG
VCQWAIQFRPRYGKPAEPTETFWKFFLEPETSLPPNDSRSPEFRRLQAFE
AAAGINGAAALDDPAFTNELRDSILAVASRPKTKEAQRLFSRLKDYQPAH
RMILAKVAAEWIESRYRRAHQNWERNYEEWKKEKQEWEQNHPELTPEIRE
AFNQIFQQLEVKEKRVRICPAARLLQNKDNCQYAGKNKHSVLCNQFNEFK
KNHLQGKAIKFFYKDAEKYLRCGLQSLKPNVQGPFREDWNKYLRYMNLKE
ETLRGKNGGRLPHCKNLGQECEFNPHTALCKQYQQQLSSRPDLVQHDELY
RKWRREYWREPRKPVFRYPSVKRHSIAKIFGENYFQADFKNSVVGLRLDS
MPAGQYLEFAFAPWPRNYRPQPGETEISSVHLHFVGTRPRIGFRFRVPHK
RSRFDCTQEELDELRSRTFPRKAQDQKFLEAARKRLLETFPGNAEQELRL
LAVALGTDSARAAFFIGKTFQQAFPLKIVKIEKLYTVHTARMIRDWARLN
ARQIIQLAEENQVDLIVLESLRGFRPPGYENLDQEKKRRVAFFAHGRIRR
KVTEKAVERGMRVVTVPYLASSVDENAARVLGRVFWGEI
3D structure
PDB8i16 Structural transitions upon guide RNA binding and their importance in Cas12g-mediated RNA cleavage.
ChainA
Resolution2.24 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 ZN A C228 C240 H335 C339 C219 C231 H326 C330
BS02 ZN A H248 C252 C323 C330 H239 C243 C314 C321
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0046872 metal ion binding

View graph for
Molecular Function
External links
PDB RCSB:8i16, PDBe:8i16, PDBj:8i16
PDBsum8i16
PubMed37729124
UniProtA0A7C2YU39

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