Structure of PDB 8i06 Chain A

Receptor sequence
>8i06A (length=244) Species: 90371 (Salmonella enterica subsp. enterica serovar Typhimurium) [Search protein sequence]
PPCEELEIVWKNIKAEARALADCEPMLASFYHATLLKHENLGSALSYMLA
NKLASPIMPAIAIREVVEEAYAADPEMIASAACDIQAVRTRDPAVDKYST
PLLYLKGFHALQAYRIGHWLWNKGRRALAIFLQNQVSVSFQVDIHPAAKI
GRGIMLDHATGIVVGETAVIEDDVSILQSVTLGGTGKTSGDRHPKIREGV
MIGAGAKILGNIEVGRGAKIGAGSVVLQPVPPHTTAAGVPARIV
3D structure
PDB8i06 Alkyl gallates inhibit serine O -acetyltransferase in bacteria and enhance susceptibility of drug-resistant Gram-negative bacteria to antibiotics.
ChainA
Resolution2.5 Å
3D
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Enzymatic activity
Enzyme Commision number 2.3.1.30: serine O-acetyltransferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 CYS A P93 H158 P93 H158
BS02 COA A H158 L177 Q178 G203 A204 G221 A222 T235 A237 H158 L177 Q178 G203 A204 G221 A222 T235 A237
Gene Ontology
Molecular Function
GO:0009001 serine O-acetyltransferase activity
GO:0016740 transferase activity
GO:0016746 acyltransferase activity
GO:0016747 acyltransferase activity, transferring groups other than amino-acyl groups
Biological Process
GO:0006535 cysteine biosynthetic process from serine
GO:0008652 amino acid biosynthetic process
GO:0019344 cysteine biosynthetic process
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol

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Cellular Component
External links
PDB RCSB:8i06, PDBe:8i06, PDBj:8i06
PDBsum8i06
PubMed37965540
UniProtA0A0D6I3Y9

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