Structure of PDB 8i04 Chain A

Receptor sequence
>8i04A (length=258) Species: 90371 (Salmonella enterica subsp. enterica serovar Typhimurium) [Search protein sequence]
ELEIVWKNIKAEARALADCEPMLASFYHATLLKHENLGSALSYMLANKLA
SPIMPAIAIREVVEEAYAADPEMIASAACDIQAVRTRDPAVDKYSTPLLY
LKGFHALQAYRIGHWLWNKGRRALAIFLQNQVSVSFQVDIHPAAKIGRGI
MLDHATGIVVGETAVIEDDVSILQSVTLGGTGKTSGDRHPKIREGVMIGA
GAKILGNIEVGRGAKIGAGSVVLQPVPPHTTAAGVPARIVGKPGSDKPSM
DMDQHFNG
3D structure
PDB8i04 Alkyl gallates inhibit serine O -acetyltransferase in bacteria and enhance susceptibility of drug-resistant Gram-negative bacteria to antibiotics.
ChainA
Resolution2.3 Å
3D
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Enzymatic activity
Enzyme Commision number 2.3.1.30: serine O-acetyltransferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 SER A D92 P93 D157 H158 D88 P89 D153 H154
BS02 SER A G184 R192 H193 G180 R188 H189
Gene Ontology
Molecular Function
GO:0009001 serine O-acetyltransferase activity
GO:0016740 transferase activity
GO:0016746 acyltransferase activity
GO:0016747 acyltransferase activity, transferring groups other than amino-acyl groups
Biological Process
GO:0006535 cysteine biosynthetic process from serine
GO:0008652 amino acid biosynthetic process
GO:0019344 cysteine biosynthetic process
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol

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Molecular Function
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Cellular Component
External links
PDB RCSB:8i04, PDBe:8i04, PDBj:8i04
PDBsum8i04
PubMed37965540
UniProtA0A0D6I3Y9

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