Structure of PDB 8hzy Chain A

Receptor sequence
>8hzyA (length=462) Species: 9606 (Homo sapiens) [Search protein sequence]
APAERCAHPGADLGAAVHAVGQTLAAGGLVPPDEAGTTARHLVRLAVRYG
NSPFTPLEEARHDLGVDRDAFRRLLALFGQVPELRTAVETGPAGAYWKNT
LLPLEQRGVFDAALARKPVFPYSVGLYPGPTCMFRCHFCVRVTGARYDPS
ALDAGNAMFRSVIDEIPAGNPSAMYFSGGLEPLTNPGLGSLAAHATDHGL
RPTVYTNSFALTERTLERQPGLWGLHAIRTSLYGLNDEEYEQTTGKKAAF
RRVRENLRRFQQLRAERESPINLGFAYIVLPGRASRLLDLVDFIADLNDA
GQGRTIDFVNIREDAELQEALNAFEERVRERTPGLHIDYGYALNSLRTGA
DAELLRIKPATMRPTAHPQVAVQVDLLGDVYLYREAGFPDLDGATRYIAG
RVTPDTSLTEVVRDFVERGGEVAAVDGDEYFMDGFDQVVTARLNQLERDA
ADGWEEARGFLR
3D structure
PDB8hzy Mechanistic Insights from the Crystal Structure and Computational Analysis of the Radical SAM Deaminase DesII.
ChainA
Resolution2.03979 Å
3D
structure
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Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 SF4 A C141 F143 C145 C148 R150 L189 Y242 C132 F134 C136 C139 R141 L180 Y233
External links
PDB RCSB:8hzy, PDBe:8hzy, PDBj:8hzy
PDBsum8hzy
PubMed38943270
UniProtQ9ZGH1|DESII_STRVZ dTDP-4-amino-4,6-dideoxy-D-glucose ammonia-lyase (Gene Name=desII)

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