Structure of PDB 8hz5 Chain A

Receptor sequence
>8hz5A (length=350) Species: 324602 (Chloroflexus aurantiacus J-10-fl) [Search protein sequence]
IRKVLVANRGEIAVRIIRACQELGIRTVVAYSTADRDSLAVRLADEAVCI
GPPPAAKSYLNAPALISAALVSGCDAIHPGYGFLSENPYFAEMCADCKLT
FIGPPPEPIRLMGDKAIGRETMRKAGVPTVPSLEEAIDVARQIVRHVEIQ
VLADQYGHAIHLGERDCKIVEEAPSPAVTPELRERMGADAVRGIKSIGYV
NAGTLEFLLDQDGNYYFIEMNTRIQVEHPVTEQVTGIDLVRWQLLIASGE
RLTLRQEDIKITRHAIECRINAEVEFYLPPGGPGVRVDSHLYSGYTPPGT
YDSLLAKIITFGDTRDEALNRMRRALNECVITGIKTTIPFQLALIDDPEF
3D structure
PDB8hz5 The homodimer of a biotin carboxylase isoform from chloroflexus aurantiacus
ChainA
Resolution3.0 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 6.3.4.14: biotin carboxylase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 BCT A R292 Q294 V295 E296 R223 Q225 V226 E227
Gene Ontology
Molecular Function
GO:0003989 acetyl-CoA carboxylase activity
GO:0004075 biotin carboxylase activity
GO:0005524 ATP binding
GO:0016874 ligase activity
GO:0046872 metal ion binding
Biological Process
GO:0006099 tricarboxylic acid cycle
GO:0006633 fatty acid biosynthetic process
GO:2001295 malonyl-CoA biosynthetic process

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Molecular Function
View graph for
Biological Process
External links
PDB RCSB:8hz5, PDBe:8hz5, PDBj:8hz5
PDBsum8hz5
PubMed38572988
UniProtA9WKH8

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