Structure of PDB 8hz2 Chain A

Receptor sequence
>8hz2A (length=157) Species: 9606 (Homo sapiens) [Search protein sequence]
QGYDVEFDPPLESKYECPICLMALREAVQTPCGHRFCKACIIKSIRDAGH
KCPVDNEILLENQLFPDNFAKREILSLMVKCPNEGCLHKMELRHLEDHQA
HCEFALMDCPQCQRPFQKFHINIHILKDCPRRQVSCDNCAASMAFEDKEI
HDQNCPL
3D structure
PDB8hz2 Tumor Necrosis Factor Receptor Associated Factor 6 (TRAF6) N-terminal Domain
ChainA
Resolution2.6 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.3.2.27: RING-type E3 ubiquitin transferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZN A C70 C73 C90 C93 C17 C20 C37 C40
BS02 ZN A C85 H87 C105 D108 C32 H34 C52 D55
BS03 ZN A C134 C139 H151 C81 C86 H98
BS04 ZN A C162 H177 C182 C109 H124 C129
BS05 ZN A C189 C192 H204 C208 C136 C139 H151 C155
Gene Ontology
Molecular Function
GO:0004842 ubiquitin-protein transferase activity
GO:0005164 tumor necrosis factor receptor binding
GO:0008270 zinc ion binding
Biological Process
GO:0016567 protein ubiquitination

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Molecular Function
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Biological Process
External links
PDB RCSB:8hz2, PDBe:8hz2, PDBj:8hz2
PDBsum8hz2
PubMed
UniProtQ9Y4K3|TRAF6_HUMAN TNF receptor-associated factor 6 (Gene Name=TRAF6)

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