Structure of PDB 8hyk Chain A

Receptor sequence
>8hykA (length=306) Species: 1151187 (Enterococcus faecalis EnGen0062) [Search protein sequence]
SKFSESTLSGWTKPASVTEEDRIENTISMIKSAIKNDNNFDNLVYEVFVQ
GSYGNNTNVRTNSDIDVNIMLTSTFYSKYPEGKTNSDYGFTDGTITYNEY
KNLILTALTNKFGTGNVTVGNKSIKITSNSYRVEADCIPSLLYRNYEYEN
SSSPNNYIEGIKYFASDNTSVVNYPKVHINNGIEKNNQTHKNYKRLVRVI
KRLRNKMTAENHFTNENITSFLIECLIWNVPNNYINDYDTWDETIKQTLI
FIKSSINDNSYKNWTEVSGMFYLFHNNRKWTSDDVSSFVNSLWSFMEYLE
HHHHHH
3D structure
PDB8hyk Crystal structure and functional implications of cyclic di-pyrimidine-synthesizing cGAS/DncV-like nucleotidyltransferases.
ChainA
Resolution2.021 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.7.-
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 NE0 A G52 S53 D67 K123 N174 F222 G51 S52 D66 K122 N173 F221
Gene Ontology
Molecular Function
GO:0000166 nucleotide binding
GO:0016779 nucleotidyltransferase activity
GO:0046872 metal ion binding
Biological Process
GO:0009117 nucleotide metabolic process
GO:0051607 defense response to virus

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Molecular Function

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Biological Process
External links
PDB RCSB:8hyk, PDBe:8hyk, PDBj:8hyk
PDBsum8hyk
PubMed37604815
UniProtP0DX98|CDNE_ENTF2 Cyclic dipyrimidine nucleotide synthase CdnE (Gene Name=cdnE)

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