Structure of PDB 8hwd Chain A

Receptor sequence
>8hwdA (length=308) Species: 10244 (Monkeypox virus) [Search protein sequence]
GNKLFNIAQRILDTNSVLLTERGDHIVWINNSWKFNSEEPLITKLILSIR
HQLPKEYSSELLCPRKRKTVEANIRDMLVDSVETDTYPDKLPFKNGVLDL
VDGMFYSGDDAKKYTCTVSTGFKFDDTKFVEDSPEMEELMNIINDIQPLT
DENKKNRELYEKTLSSCLCGATKGCLTFFFGETATGKSTTKRLLKSAIGD
LFVETGQTILPFIANMHLKRSVFCRSDNIKKLTEPCVNRNHATIIIDNAL
MRRIAVVRFRTHFSYDKVKLLDEGLDGKIQNNRYRFAFLYLLVKWYKKYH
IPIMKLYP
3D structure
PDB8hwd Structural insight into the assembly and working mechanism of helicase-primase D5 from Mpox virus.
ChainA
Resolution3.3 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.6.4.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ADP A I464 D467 A506 T507 G508 K509 T511 R514 F630 L650 D652 D656 I142 D145 A184 T185 G186 K187 T189 R192 F263 L270 D272 D276
Gene Ontology
Molecular Function
GO:0004386 helicase activity
GO:0005524 ATP binding
GO:0016787 hydrolase activity
Cellular Component
GO:0030430 host cell cytoplasm

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Molecular Function
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Cellular Component
External links
PDB RCSB:8hwd, PDBe:8hwd, PDBj:8hwd
PDBsum8hwd
PubMed38177671
UniProtA0A7H0DN89|PG117_MONPV Uncoating factor OPG117 (Gene Name=OPG117)

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