Structure of PDB 8hs5 Chain A

Receptor sequence
>8hs5A (length=230) Species: 224914 (Brucella melitensis bv. 1 str. 16M) [Search protein sequence]
SPFHLNDAVAIVTGAAAGIGRAIAGTFAKAGASVVVTDLKSEGAEAVAAA
IRQAGGKAIGLECNVTDEQHREAVIKAALDQFGKITVLVNNAGGGGPKPF
DMPMSDFEWAFKLNLFSLFRLSQLAAPHMQKAGGGAILNISSMAGENTNV
RMASYGSSKAAVNHLTRNIAFDVGPMGIRVNAIAPGAIKLKHTPLGRLGE
AQDIANAALFLCSPAAAWISGQVLTVSGGG
3D structure
PDB8hs5 Structure of 7-alpha-hydroxysteroid dehydrogenase
ChainA
Resolution2.3 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 1.1.1.159: 7alpha-hydroxysteroid dehydrogenase.
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 NAD A G67 D91 L92 C116 N117 V118 N144 A145 I193 S194 S195 Y208 K212 G14 D38 L39 C63 N64 V65 N91 A92 I140 S141 S142 Y155 K159
Gene Ontology
Molecular Function
GO:0016491 oxidoreductase activity

View graph for
Molecular Function
External links
PDB RCSB:8hs5, PDBe:8hs5, PDBj:8hs5
PDBsum8hs5
PubMed
UniProtQ8YIN7

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