Structure of PDB 8hs0 Chain A

Receptor sequence
>8hs0A (length=570) Species: 3702 (Arabidopsis thaliana) [Search protein sequence]
QSVTADPSPPITNKLNKYSSRITEPKSQGGSQAILHGVGLSDDDLLKPQI
GISSVWYEGNTCNMHLLKLSEAVKEGVENAGMVGFRFNTIGVSDAISMGT
RGMCFSLQSRDLIADSIETVMSAQWYDGNISIPGCDKNMPGTIMAMGRLN
RPGIMVYGGTIKPGHFQDKTYDIWSAFQSYGEFVSGSISDEQRKTVLHHS
CPGAGACGGMYTANTMASAIEAMGMSLPYSSSIPAEDPLKLDECRLAGKY
LLELLKMDLKPRDIITPKSLRNAMVSVMALGGSTNAVLHLIAIARSVGLE
LTLDDFQKVSDAVPFLADLKPSGKYVMEDIHKIGGTPAVLRYLLELGLMD
GDCMTVTGQTLAQNLENVPSLTEGQEIIRPLSNPIKETGHIQILRGDLAP
DGSVAKITGKEGLYFSGPALVFEGEESMLAAISADPMSFKGTVVVIRGEG
PKGGPGMPEMLTPTSAIMGAGLGKECALLTDGRFSGGSHGFVVGHICPEA
QEGGPIGLIKNGDIITIDIGAARIDTQVSPEEMNDRRKKWTAPAYKVNRG
VLYKYIKNVQSASDGCVTDE
3D structure
PDB8hs0 The mutant structure of DHAD
ChainA
Resolution1.42 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 4.2.1.9: dihydroxy-acid dehydratase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 FES A C66 D98 A99 C139 D140 C211 C62 D94 A95 C135 D136 C207
BS02 MG A D140 K141 N289 H293 D136 K137 N285 H289
Gene Ontology
Molecular Function
GO:0003824 catalytic activity
GO:0004160 dihydroxy-acid dehydratase activity
GO:0005507 copper ion binding
GO:0016829 lyase activity
GO:0016836 hydro-lyase activity
GO:0046872 metal ion binding
GO:0051537 2 iron, 2 sulfur cluster binding
Biological Process
GO:0008652 amino acid biosynthetic process
GO:0009082 branched-chain amino acid biosynthetic process
GO:0009097 isoleucine biosynthetic process
GO:0009099 L-valine biosynthetic process
GO:0009553 embryo sac development
GO:0009555 pollen development
GO:0009651 response to salt stress
GO:0048364 root development
Cellular Component
GO:0005829 cytosol
GO:0009507 chloroplast
GO:0009536 plastid
GO:0009570 chloroplast stroma

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8hs0, PDBe:8hs0, PDBj:8hs0
PDBsum8hs0
PubMed
UniProtQ9LIR4|ILVD_ARATH Dihydroxy-acid dehydratase, chloroplastic (Gene Name=DHAD)

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