Structure of PDB 8hrv Chain A

Receptor sequence
>8hrvA (length=144) Species: 85962 (Helicobacter pylori 26695) [Search protein sequence]
AMKIKIQKIHPNALIPKYQTDGSSGFDLHAVEEVMIKPHSVGLVKIGICL
SLEVGYELQVRTRSGLALNHQVMVLNSPGTVDNDYRGEIKVILANLSDKD
FKVQVGDRIAQGVVQKTYKAEFIECEQLDETSRGSGGFGSTGVS
3D structure
PDB8hrv dutpase of helicobacter pylori 26695
ChainA
Resolution2.0 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.6.1.23: dUTP diphosphatase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 DUP A R132 G136 F137 G138 S139 T140 R133 G137 F138 G139 S140 T141
BS02 DUP A R62 S63 G64 Q110 R63 S64 G65 Q111
BS03 DUP A N75 T79 D81 Y84 K89 N76 T80 D82 Y85 K90
Gene Ontology
Molecular Function
GO:0000287 magnesium ion binding
GO:0004170 dUTP diphosphatase activity
GO:0016787 hydrolase activity
GO:0046872 metal ion binding
Biological Process
GO:0006226 dUMP biosynthetic process
GO:0009117 nucleotide metabolic process
GO:0046081 dUTP catabolic process

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Molecular Function
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Biological Process
External links
PDB RCSB:8hrv, PDBe:8hrv, PDBj:8hrv
PDBsum8hrv
PubMed
UniProtO25536|DUT_HELPY Deoxyuridine 5'-triphosphate nucleotidohydrolase (Gene Name=dut)

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