Structure of PDB 8hrp Chain A

Receptor sequence
>8hrpA (length=334) Species: 196627 (Corynebacterium glutamicum ATCC 13032) [Search protein sequence]
TIRVGINGFGRIGRNFFRAVLERSDDLEVVAVNDLTDNKTLSTLLKFDSI
MGRLGQEVEYDDDSITVGGKRIAVYAERDPKNLDWAAHNVDIVIESTGFF
TDANAAKAHIEAGAKKVIISAPASNEDATFVYGVNHESYDPENHNVISGA
SCTTNCLAPMAKVLNDKFGIENGLMTTVHAYTGDQRLHDAPHRDLRRARA
AAVNIVPTSTGAAKAVALVLPELKGKLDGYALRVPVITGSATDLTFNTKS
EVTVESINAAIKEAAVGEFGETLAYSEEPLVSTDIVHDSHGSIFDAGLTK
VSGNTVKVVSWYDNEWGYTCQLLRLTELVASKLL
3D structure
PDB8hrp Structure-Guided Protein Engineering of Glyceraldehyde-3-phosphate Dehydrogenase from Corynebacterium glutamicum for Dual NAD/NADP Cofactor Specificity.
ChainA
Resolution1.99 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 1.2.1.12: glyceraldehyde-3-phosphate dehydrogenase (phosphorylating).
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 NAD A G11 R12 I13 D35 L36 R79 S97 T98 G99 S121 C153 N315 Y319 G10 R11 I12 D34 L35 R78 S96 T97 G98 S120 C152 N314 Y318
BS02 G3H A S152 C153 T154 H180 T211 S151 C152 T153 H179 T210
Gene Ontology
Molecular Function
GO:0000166 nucleotide binding
GO:0004365 glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
GO:0016491 oxidoreductase activity
GO:0016620 oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
GO:0050661 NADP binding
GO:0051287 NAD binding
Biological Process
GO:0006006 glucose metabolic process
GO:0006096 glycolytic process
Cellular Component
GO:0005737 cytoplasm

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8hrp, PDBe:8hrp, PDBj:8hrp
PDBsum8hrp
PubMed37935620
UniProtQ01651|G3P_CORGL Glyceraldehyde-3-phosphate dehydrogenase (Gene Name=gap)

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