Structure of PDB 8hrh Chain A

Receptor sequence

>8hrhA (length=214) Species: 10090 (Mus musculus) [Search protein sequence]

QVQLQQSGAELARPGASVKLSCKASGYTFTNYGLSWVKQRTGQGLEWIGE
NHPGSGIIYHNEKFRGKATLTADKSSSTAYVQLSSLTSEDSAVYFCARSS
GTRGFAYWGQGTLVTVSAAKTTAPSVYPLAPVCGSSVTLGCLVKGYFPEP
VTLTWNSGSLSSGVHTFPAVLQSDLYTLSSSVTVTSSTWPSQSITCNVAH
PASSTKVDKKIEPR

3D structure

PDB

8hrh Structural and molecular insight into antibody recognition of dynamic neoepitopes in membrane tethered MUC1 of pancreatic cancer cells and secreted exosomes.

Chain

Resolution

2.07 Å

3D
structure

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Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	ASP	A	N31 Y32 S100 G101 T102	N31 Y32 S100 G101 T102
BS02	ARG	A	Y59 S99 G101 G104 F105	Y59 S99 G101 G104 F105

External links

PDB	RCSB:8hrh, PDBe:8hrh, PDBj:8hrh
PDBsum	8hrh
PubMed	37547453

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