Structure of PDB 8hqy Chain A

Receptor sequence
>8hqyA (length=97) Species: 9606 (Homo sapiens) [Search protein sequence]
PHRYRPGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSS
AVMALQEASEAYLVGLFEDTNLSAIHAKRVTIMPKDIQLARRIRGER
3D structure
PDB8hqy A Cryptic Basic Groove formed by Ubiquitin and Histone H3 Mediates Selective Recognition of H2AK119Ub Nucleosomes by Synovial Sarcoma X Breakpoint 1 Protein.
ChainA
Resolution3.05 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 dna A R40 Y41 P43 G44 V46 R49 R63 K64 L65 R3 Y4 P6 G7 V9 R12 R26 K27 L28
BS02 dna A R40 Y41 R42 R72 R83 F84 Q85 V117 T118 R3 Y4 R5 R35 R46 F47 Q48 V80 T81
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0030527 structural constituent of chromatin
GO:0046982 protein heterodimerization activity
Cellular Component
GO:0000786 nucleosome

View graph for
Molecular Function

View graph for
Cellular Component
External links
PDB RCSB:8hqy, PDBe:8hqy, PDBj:8hqy
PDBsum8hqy
PubMed38177667
UniProtQ71DI3|H32_HUMAN Histone H3.2 (Gene Name=H3C15)

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