Structure of PDB 8hp7 Chain A

Receptor sequence
>8hp7A (length=241) Species: 1206458 (Novosphingobium sp. MBES04) [Search protein sequence]
MRLGDYKALSFDCYGTLIDWESGMIEGLRELTARVGTDMSRDEILQAHAR
HESRQQAQTPGKPYRDLLPIVYKRLAEQWGVPFSQAECEEYGRSVRNWPA
FVDSPGALQYLKKYYKLIILSNVDNKTFQYSNEKLQVEFDAIYSAEDVGA
YAPSDRNFEYMNGHIGDLGLEPGDILHTAESLFHDHVPARKFGMANCWIY
RRHAQEGFGATMTPSHEPTYDFRFNSMADLVKAHQEELRNG
3D structure
PDB8hp7 Enzymatic hydrolysis on L-azetidine-2-carboxylate ring opening
ChainA
Resolution1.43 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.8.1.2: (S)-2-haloacid dehalogenase.
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 ABU A D12 C13 Y14 W20 S121 N122 H184 D12 C13 Y14 W20 S121 N122 H184
Gene Ontology
Molecular Function
GO:0016787 hydrolase activity
GO:0018784 (S)-2-haloacid dehalogenase activity
GO:0019120 hydrolase activity, acting on acid halide bonds, in C-halide compounds

View graph for
Molecular Function
External links
PDB RCSB:8hp7, PDBe:8hp7, PDBj:8hp7
PDBsum8hp7
PubMed
UniProtA0A0S6WSA3

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