Structure of PDB 8hog Chain A

Receptor sequence
>8hogA (length=144) Species: 9606 (Homo sapiens) [Search protein sequence]
YDNREIVMKYIHYKLSQRGYEWDAGDDVESEVVHLTLRQAGDDFSRRYRR
DFAEMSSQLHLTPFTARGRFATVVEELFRDGVNWGRIVAFFEFGGVMCVE
SVNREMSPLVDNIALWMTEYLNRHLHTWIQDNGGWDAFVELYGP
3D structure
PDB8hog Crystal structure of Bcl-2 in complex with sonrotoclax
ChainA
Resolution1.8 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 98I A A100 D103 F104 R107 Y108 D111 F112 M115 N143 W144 G145 F198 Y202 A40 D43 F44 R47 Y48 D51 F52 M55 N83 W84 G85 F138 Y142
Gene Ontology
Biological Process
GO:0042981 regulation of apoptotic process

View graph for
Biological Process
External links
PDB RCSB:8hog, PDBe:8hog, PDBj:8hog
PDBsum8hog
PubMed38211332
UniProtP10415|BCL2_HUMAN Apoptosis regulator Bcl-2 (Gene Name=BCL2)

[Back to BioLiP]