Structure of PDB 8hnq Chain A

Receptor sequence
>8hnqA (length=286) Species: 2664417 (Devosia sp. D6-9) [Search protein sequence]
PRGSHMSEPNAALAGQFKIGGDLTINRLGFGAMRITGEGIWGQPKDVEEA
RRVLRRLKALGVNFVDTAESYGPEVSEQLIADELYPYDGFVIATKAGLQR
PGPNHWVQDGRPEVLRRGLEASLKRLKVERIDLWQLHRIDSKVPRDEQFA
AIAGFVKDGLVRHVGLSEVTVEEIEAAQKYFPVATIQNRYNLFDRASEEE
LEFCEANAIGFIPWAPLASGRVGGRPVLEAVAQRHGASPGQIALAWMLKR
SPVILPIPGTGKVAHLEENVAAAGITLSEGDMAELE
3D structure
PDB8hnq The structure of AKR13B2
ChainA
Resolution2.0 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 NAP A G26 M28 R29 Y66 R133 Q182 W209 A210 P211 L212 S214 G215 I252 P253 G254 T255 K257 H260 E263 N264 G31 M33 R34 Y71 R138 Q187 W214 A215 P216 L217 S219 G220 I257 P258 G259 T260 K262 H265 E268 N269
BS02 O4B A L93 W101 R133 L98 W106 R138
Gene Ontology
Molecular Function
GO:0000166 nucleotide binding
GO:0004033 aldo-keto reductase (NADPH) activity
GO:0016491 oxidoreductase activity
Cellular Component
GO:0005737 cytoplasm

View graph for
Molecular Function
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Cellular Component
External links
PDB RCSB:8hnq, PDBe:8hnq, PDBj:8hnq
PDBsum8hnq
PubMed
UniProtA0A6B8QJ47

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