Structure of PDB 8hkr Chain A

Receptor sequence
>8hkrA (length=378) Species: 83332 (Mycobacterium tuberculosis H37Rv) [Search protein sequence]
HRWLYPHPIADLEAWTTANWEWFDPVHSHRILWPDREYRPDLDILIAGCG
TNQAAIFAFTNRAAKVVAIDISRPALDHQQYLKDKHGLANLELHLLPIEE
LATLGRDFDLVVSTGVLHHLADPRAGMKELAHCLRRDGVVAAMLYGKYGR
IGVELLGSVFRDLGLGQDDASIKLAKEAISLLPTYHPLRNYLTSDSALVD
TFLHGRQRSYTVEECVDLVTSAGLVFQGWFHKAPYYPHDFFVPNSEFYAA
VNTLPEVKAWSVMERLETLNATHLFMACRRDRPKEQYTIDFSTVAALDYV
PLMRTRCGVSGTDMFWPGWRMAPSPAQLAFLQQVDGRRTIREIAGCVART
SLADLEEFGRKLFQSLWRLDFVAVALPA
3D structure
PDB8hkr Crystal Structure of Histone H3 Lysine 79 (H3K79) Methyltransferase Rv2067c from Mycobacterium tuberculosis
ChainA
Resolution2.4 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 SAH A G63 G65 Q68 D85 P112 I113 T129 V131 L135 G48 G50 Q53 D70 P97 I98 T114 V116 L120
Gene Ontology
Molecular Function
GO:0008168 methyltransferase activity
Cellular Component
GO:0005886 plasma membrane
GO:0009274 peptidoglycan-based cell wall

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Molecular Function
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Cellular Component
External links
PDB RCSB:8hkr, PDBe:8hkr, PDBj:8hkr
PDBsum8hkr
PubMed38129415
UniProtP9WLL9|Y2067_MYCTU Uncharacterized protein Rv2067c (Gene Name=Rv2067c)

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