Structure of PDB 8hjl Chain A

Receptor sequence

>8hjlA (length=427) Species: 190515 (Siraitia grosvenorii) [Search protein sequence]

TTTILMLPWLGYGHLSAFLELAKSLSRRNFHIYFCSTSVNLDAIKPKLPS
SFSDSIQFVELHLPSSPEFPPHLHTTNGLPPTLMPALHQAFSMAAQHFES
ILQTLAPHLLIYDSLQPWAPRVASSLKIPAINFNTTGVFVISQGLHPIHY
PHSKFPFSEFVLHNHWKATERTRKRGEAFLYCLHASCSVILINSFRELEG
KYMDYLSVLLNKKVVPVGPLVYEPNDEGYSSIKNWLDKKEPSSTVFVSFG
SEYFPSKEEMEEIAHGLEASEVNFIWVVRFPQALPKGFLERAGERGMVVK
GWAPQAKILKHWSTGGFVSHCGWNSVMESMMFGVPIIGVPMHVDQPFNAG
LVEEAGVGVEAKRDPDGKIQRDEVAKLIKEVVVEKTREDVRKKAREMSEI
LRSKGEEKFDEMVAEISLLLKIEHHHH

3D structure

PDB

8hjl Structural insights into the catalytic selectivity of SgUGT94-289-3 towards mogrosides

Chain

Resolution

1.72 Å

3D
structure

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Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)
BS01	UDP	A	Y20 S272 V298 W332 A333 Q335 H350 G352 N354 S355 E358	Y12 S251 V277 W302 A303 Q305 H320 G322 N324 S325 E328
BS02	POG	A	V148 Q151 G152 I156 R190 G193 E194 L197 F377	V140 Q143 G144 I148 R173 G176 E177 L180 F347
BS03	M7F	A	R129 H157 L197 Y198 H201 L226	R121 H149 L180 Y181 H184 L209
BS04	M7F	A	M92 H96 L123 R192 A195 F196 V373	M84 H88 L115 R175 A178 F179 V343

External links

PDB	RCSB:8hjl, PDBe:8hjl, PDBj:8hjl
PDBsum	8hjl
PubMed	39080270

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