Structure of PDB 8hip Chain A

Receptor sequence
>8hipA (length=647) Species: 9606 (Homo sapiens) [Search protein sequence]
SVLVFEISSKMKMIEKKLEANTVHVLRLELDQSFILDLTKVAAEIVDSSK
YSKEDGVILEVTVSNGRDSFLLKLPTVYPNLKLYTDGKLLNPLVEQDFHF
HQNLIVTVQSRLNADIDYRLHVTHLDRAQYDFLKFKTGQTTKTLSNQKLT
FVKPIGFFLNCSEQNISQFHVTLYSEDDICANLITVPANESIYDRSVISD
KTHNRRVLSFTKRADIFFTETEISMFKSFRIFVFIAPDDSGCSTNTSRKS
FNEKKKISFEFKKLENQSYAVPTALMMIFLTTPCLLFLPIVINIIKNSRS
LHGQMLQYPVAIILPVLMHTAIEFHKWTTSTMANRDEMCFHNHACARPLG
ELRAWNNIITNIGYTLYGAIFIVLSICRRGSHVFGTYECTLLDVTIGVFM
VLQSIASATYHICPSDVAFQFDTPCIQVICGLLMVRQWFVRHESPSPAYT
NILLVGVVSLNFLISAFSKTSYVRFIIAVIHVIVVGSICLAKERSLGSEK
LKTRFFIMAFSMGNFAAIVMYLTLSAFHLNQIATYCFIINCIMYLMYYGC
MKVLHSERITSKAKLCGALSLLAWAVAGFFFFQDDTDWTRSAAASRALNK
PCLLLGFFGSHDLWHIFGALAGLFTFIFVSFVDDDLINTRKTSINIF
3D structure
PDB8hip Structure of dsRNA transporter at 2.77 Angstroms resolution.
ChainA
Resolution2.77 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 6OU A M563 W567 F568 F666 M434 W438 F439 F537
BS02 6OU A G585 L589 I609 V613 A620 R623 G456 L460 I480 V484 A491 R494
BS03 ZN A H540 D551 H740 H744 H411 D422 H611 H615
Gene Ontology

View graph for
Cellular Component
External links
PDB RCSB:8hip, PDBe:8hip, PDBj:8hip
PDBsum8hip
PubMed38664565
UniProtQ9GZC8|SID1_CAEEL Systemic RNA interference defective protein 1 (Gene Name=sid-1)

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