Structure of PDB 8hfc Chain A

Receptor sequence
>8hfcA (length=276) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence]
PLWLGVLLAIVCPMVLFSIFEAHKLWHTQNGYKVLVIFFYYFWVITLASF
IRTATSDPGVLPRNIHLSQLRNNYQIPQEYYNLITLPTHSSISKDITIKY
CPSCRIWRPPRSSHCSTCNVCVMVHDHHCIWVNNCIGKRNYRFFLIFLLG
AILSSVILLTNCAIHIARESGGPRDCPVAILLLCYAGLTLWYPAILFTYH
IFMAGNQQTTREFLKGIGSKKNPVFHRVVKEENIYNKGSFLKNMGHLMLE
PRGPSFVSARKPHEAGDWRFMDLSPA
3D structure
PDB8hfc Cryo-EM structure of Yeast Erf2/Erf4 complex
ChainA
Resolution3.5 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.3.1.225: protein S-acyltransferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZN A C189 H202 C115 H128
BS02 ZN A C178 H188 C104 H114
Gene Ontology
Molecular Function
GO:0005515 protein binding
GO:0008270 zinc ion binding
GO:0016409 palmitoyltransferase activity
GO:0016746 acyltransferase activity
GO:0019706 protein-cysteine S-palmitoyltransferase activity
Biological Process
GO:0006612 protein targeting to membrane
GO:0018345 protein palmitoylation
Cellular Component
GO:0005783 endoplasmic reticulum
GO:0005789 endoplasmic reticulum membrane
GO:0005794 Golgi apparatus
GO:0016020 membrane
GO:0031211 endoplasmic reticulum palmitoyltransferase complex
GO:0032541 cortical endoplasmic reticulum
GO:0097038 perinuclear endoplasmic reticulum

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Cellular Component
External links
PDB RCSB:8hfc, PDBe:8hfc, PDBj:8hfc
PDBsum8hfc
PubMed38182928
UniProtQ06551|ERFB_YEAST Palmitoyltransferase ERF2 (Gene Name=ERF2)

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