Structure of PDB 8hen Chain A

Receptor sequence
>8henA (length=255) Species: 9606 (Homo sapiens) [Search protein sequence]
KLPASFDAREQWPQCPTIKEIRDQGSCGSCWAFGAVEAISDRICIHTNAH
VSVEVSAEDLLTCCGSMCGDGCNGGYPAEAWNFWTRKGLVSGGLYESHVG
CRPYSIPPCEHHVNGSRPPCTGEGDTPKCSKICEPGYSPTYKQDKHYGYN
SYSVSNSEKDIMAEIYKNGPVEGAFSVYSDFLLYKSGVYQHVTGEMMGGH
AIRILGWGVENGTPYWLVANSWNTDWGDNGFFKILRGQDHCGIESEVVAG
IPRTD
3D structure
PDB8hen Crystal structure of CTSB in complex with 212-148
ChainA
Resolution1.95 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.4.22.1: cathepsin B.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 L4F A C29 N72 G73 G74 Y75 G121 G198 H199 W221 C30 N73 G74 G75 Y76 G122 G199 H200 W222
Gene Ontology
Molecular Function
GO:0008234 cysteine-type peptidase activity
Biological Process
GO:0006508 proteolysis

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Molecular Function
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Biological Process
External links
PDB RCSB:8hen, PDBe:8hen, PDBj:8hen
PDBsum8hen
PubMed37990007
UniProtP07858|CATB_HUMAN Cathepsin B (Gene Name=CTSB)

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