Structure of PDB 8haw Chain A

Receptor sequence
>8hawA (length=479) Species: 3702 (Arabidopsis thaliana) [Search protein sequence]
YPIKTIVVLVQENRSFDHTLGWFKELNREIDGVTKSDPKSNTVSNSLRVV
FGDQSQYVNPDPGHSIQDIYEQVFGKPWDSGKPDPNPGHPNMSGFAQNAE
RNKKGMSSAVMNGFKPNALPVYKELVQNFAICDRWFASVPASTQPNRLYV
HSATSHGATSNDAALLLEGFPQKTIFESLDEAGFSFGIYYQFPPSTLFYR
NLRKLKYLTHFHQYGIQFKKDCKEGKLPNYVVVEQRWFDLLSTPANDDHP
SHDVSEGQKLVKEVYEALRSSPQWNEILFIITYDEHGGFYDHVPTPVDGV
PNPDGILGPPPYNFEFNRLGVRVPTFFISPWIEPGTVIHGPNGPYPRSQY
EHSSIPATVKTIFKLKDFLSKRDSWAGTFESVITRDSPRQDCPETLSTPI
KLRGTMAKENAQLSEFQEDLVIMAAGLKGDYKNEELIHKLCKETCVADAS
KYVTNAFEKFLEESRKARDRGCDENDIVY
3D structure
PDB8haw Insights into the mechanism of phospholipid hydrolysis by plant non-specific phospholipase C.
ChainA
Resolution2.1 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.1.4.3: phospholipase C.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 CA A E23x N24x T158x D299x E300x E12 N13 T143 D284 E285
Gene Ontology
Molecular Function
GO:0004629 phospholipase C activity
GO:0016787 hydrolase activity
GO:0016788 hydrolase activity, acting on ester bonds
GO:0034480 phosphatidylcholine phospholipase C activity
Biological Process
GO:0009395 phospholipid catabolic process
Cellular Component
GO:0005886 plasma membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8haw, PDBe:8haw, PDBj:8haw
PDBsum8haw
PubMed36635324
UniProtQ9SRQ7|NPC4_ARATH Non-specific phospholipase C4 (Gene Name=NPC4)

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